BMS 986188 | δ-opioid PAM | Probechem Biochemicals

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Chemical Structure : BMS 986188

CAS No.: 1776115-10-6

BMS 986188 (BMS986188)

Catalog No.: PC-38532Not For Human Use, Lab Use Only.

BMS 986188 is a potent, selective positive allosteric modulator of δ-opioid receptor with EC50 of 0.05 uM in β-arrestin recruitment assays, no significant acitivity against μ-opioid receptors.

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10 mg	$128	In stock
25 mg	$218	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BMS 986188 is a potent, selective positive allosteric modulator of δ-opioid receptor with EC50 of 0.05 uM in β-arrestin recruitment assays, no significant acitivity against μ-opioid receptors.

Physicochemical Properties

M.Wt	535.5
Formula	C30H31BrO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	9-[4-[(2-bromophenyl)methoxy]phenyl]-3,4,5,6,7,9-hexahydro-3,3,6,6-tetramethyl-1H-xanthene-1,8(2H)-dione

References

1. Burford NT, et al. J Med Chem. 2015 May 28;58(10):4220-9.

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BMS 986188 (BMS986188)

Biological Activity

Physicochemical Properties

References

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