BMT-046091 |CAS:1551401-20-7 Probechem Biochemicals

Chemical Structure : BMT-046091

BMT-046091 (BMT046091)

Catalog No.: PC-35098Not For Human Use, Lab Use Only.

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM.

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Biological Activity

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM.
BMT-046091 is inactive in a panel of functional or binding assays for receptors, transporters and enzymes at >5 μM.
[3H]BMT-046091 is a potent and selective radioligand to determine AAK1 distribution and target engagement.

Physicochemical Properties

M.Wt	311.385
Formula	C18H21N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-8-((2-amino-4-methylpentyl)oxy)benzo[c][2,7]naphthyridin-5(6H)-one

References

1. Louis JV, et al. Neuropharmacology. 2017 May 15;118:167-174.

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BMT-046091 (BMT046091)

Biological Activity

Physicochemical Properties

References

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