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BMT-046091

Chemical Structure : BMT-046091

CAS No.: 1551401-20-7

BMT-046091 (BMT046091)

Catalog No.: PC-35098Not For Human Use, Lab Use Only.

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM.
BMT-046091 is inactive in a panel of functional or binding assays for receptors, transporters and enzymes at >5 μM.
[3H]BMT-046091 is a potent and selective radioligand to determine AAK1 distribution and target engagement.

Physicochemical Properties

M.Wt 311.385
Formula C18H21N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-8-((2-amino-4-methylpentyl)oxy)benzo[c][2,7]naphthyridin-5(6H)-one

References

1. Louis JV, et al. Neuropharmacology. 2017 May 15;118:167-174.

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