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Chemical Structure : BNBI
Catalog No.: PC-60575Not For Human Use, Lab Use Only.
BNBI is a selective renal outer medullary potassium channel (ROMK, Kir1.1) inhibitor with IC50 of 8 uM in T1+ flux assays, does not inhibit Kir7.1 at 100 uM.
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BNBI is a selective renal outer medullary potassium channel (ROMK, Kir1.1) inhibitor with IC50 of 8 uM in T1+ flux assays, does not inhibit Kir7.1 at 100 uM.
BNBI has no detectable effect on uterine contractility in the GD15 mouse at 100 uM.
| M.Wt | 366.337 | |
| Formula | C17H14N6O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bhave G, et al. Mol Pharmacol. 2011 Jan;79(1):42-50.
2. Lewis LM, et al. Mol Pharmacol. 2009 Nov;76(5):1094-103.
3. McCloskey C, et al. EMBO Mol Med. 2014 Sep;6(9):1161-74.
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