BPDBA

Chemical Structure : BPDBA

CAS No.: 312281-74-6

Catalog No.: PC-26891Not For Human Use, Lab Use Only.

BPDBA is a potent, subtype selective and noncompetitive inhibitor of betaine/GABA transporter 1 (BGT-1) with IC50 of 20 uM (hBGT-1) and 39 uM ( mouse ortholog mGAT2), shows no activity against hGAT-1/mGAT1, hGAT-2/mGAT3, and hGAT-3/mGAT4.

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Biological Activity

Physicochemical Properties

M.Wt	363.28
Formula	C19H20Cl2N2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-Benzyl-4-piperidinyl)-2,4-dichlorobenzamide

References

1. Jørgensen L, et al. J Med Chem. 2017 Nov 9;60(21):8834-8846.

2. Kragholm B, et a. Biochem Pharmacol. 2013 Aug 15;86(4):521-8.

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BPDBA

Biological Activity

Physicochemical Properties

References

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