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Chemical Structure : BPIPP
CAS No.: 325746-94-9
Catalog No.: PC-62076Not For Human Use, Lab Use Only.
BPIPP is an inhibitor of GC-C (guanylyl cyclase type C) that inhibits stimulation of guanylyl cyclase and adenylyl cyclase, suppresses cGMP accumulation in a variety of cell lines (IC50=3.4-11.2 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $188 | In stock | |
| 10 mg | $298 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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BPIPP is an inhibitor of GC-C (guanylyl cyclase type C) that inhibits stimulation of guanylyl cyclase and adenylyl cyclase, suppresses cGMP accumulation in a variety of cell lines (IC50=3.4-11.2 uM).
BPIPP inhibits chloride-ion transport stimulated by activation of guanylyl or adenylyl cyclases.
BPIPP suppresses stable toxin-induced fluid accumulation in an in vivo rabbit intestinal loop model.
| M.Wt | 450.28 | |
| Formula | C22H16BrN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-(3-bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione |
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1. Kots AY, et al. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8440-5.
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