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BPU-11

Chemical Structure : BPU-11

CAS No.: 909664-41-1

BPU-11 (Biphenyl urea compound 11)

Catalog No.: PC-38512Not For Human Use, Lab Use Only.

BPU-11 is a novel specific HCN4 channel c-linker pocket (CLP) ligand and modulator, completely abolishing the cAMP-induced shift in V1/2 (k1/2=0.42 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BPU-11 is a novel specific HCN4 channel c-linker pocket (CLP) ligand and modulator, completely abolishing the cAMP-induced shift in V1/2 (k1/2=0.42 uM).

Physicochemical Properties

M.Wt 501.63
Formula C32H31N5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-{1-[(3-Cyanophenyl)methyl]piperidin-4-yl}-3-(2-phenylphenyl)-1-(pyridin-3-ylmethyl)urea

References

1. Marco Lolicato, et al. Nat Chem Biol. 2014 Jun;10(6):457-62.

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