BPU11

Chemical Structure : BPU11

Catalog No.: PC-25880Not For Human Use, Lab Use Only.

BPU11 is a specific small molecule CD28 inhibitor targeting CD28 costimulation with Kd of 6.5 uM, disrupts CD28-B7 interactions across biochemical and cellular systems.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

BPU11 is a specific small molecule CD28 inhibitor targeting CD28 costimulation with Kd of 6.5 uM, disrupts CD28-B7 interactions across biochemical and cellular systems.
BPU11 inhibits CD28-CD80 binding in a dose-dependent manner with IC50 of 18.89 uM.
BPU11 suppresses CD28-dependent cytokine release (FN-γ, IL-2, and TNF-α) in human PBMC-mucosal co-culture model.

Physicochemical Properties

M.Wt	422.47
Formula	C18H16F2N4O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2,5-difluorophenyl)-2-((5-((2-ethoxyphenyl)amino)-1,3,4-thiadiazol-2-yl)thio)acetamide

References

1. Saurabh Upadhyay, et al. bioRxiv [Preprint]. 2025 Oct 7:2025.10.06.680836.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

BPU11

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.