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Chemical Structure : BRAF inhibitor 13
CAS No.: 1093100-40-3
Catalog No.: PC-70025Not For Human Use, Lab Use Only.
A potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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BRAF inhibitor 13 (BRAF-IN-13) is a potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
BRAF inhibitor 13 (BRAF-IN-13) induces proliferation and hyperplasia in normal tissues of mice.
| M.Wt | 478.944 | |
| Formula | C26H19ClN8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N5-(3-(9H-purin-6-yl)pyridin-2-yl)-N1-(4-chlorophenyl)-6-methylisoquinoline-1,5-diamine |
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1. Wang X, et al. J Med Chem. 2012 Sep 13;55(17):7332-41.
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