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Chemical Structure : BRAF inhibitor 13
Catalog No.: PC-70025Not For Human Use, Lab Use Only.
A potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
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A potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively; induces proliferation and hyperplasia in normal tissues of mice.
| M.Wt | 478.944 | |
| Formula | C26H19ClN8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wang X, et al. J Med Chem. 2012 Sep 13;55(17):7332-41.
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