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Chemical Structure : BRD-73954
CAS No.: 1440209-96-0
Catalog No.: PC-45534Not For Human Use, Lab Use Only.
BRD-73954 is the first potent, selective HDAC6/8 dual inhibitor with IC50s of 36/120 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $18 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $368 | In stock | |
| 100 mg | Get quote |
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BRD-73954 is the first potent, selective HDAC6/8 dual inhibitor with IC50s of 36/120 nM.
BRD-73954 show no significant inhibition for other HDAC isoforms (IC50>9 uM).
BRD-73954 robustly increase in α-tubulin acetylation, has no change in the acetylation state of H3 in Hela cells.
| M.Wt | 284.3098 | |
| Formula | C16H16N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 35 mg/mL |
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| Chemical Name/SMILES |
1,3-Benzenedicarboxamide, N1-hydroxy-N3-(2-phenylethyl)- |
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1. Olson DE, et al. J Med Chem. 2013 Jun 13;56(11):4816-20.
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