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Chemical Structure : BRD4 degrader AT1
CAS No.: 2098836-45-2
Catalog No.: PC-35351Not For Human Use, Lab Use Only.
BRD4 degrader AT1 is a highly selective BRD4 degrader (PROTAC), exhibits highly selective depletion of BRD4 in cells with negligible activity against BRD2 and BRD3.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $118 | In stock | |
| 5 mg | $288 | In stock | |
| 10 mg | $488 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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BRD4 degrader AT1 is a highly selective BRD4 degrader (PROTAC), exhibits highly selective depletion of BRD4 in cells with negligible activity against BRD2 and BRD3.
| M.Wt | 972.68 | |
| Formula | C48H58ClN9O5S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2S,4R)-1-((R)-2-acetamido-3-((6-(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)hexyl)thio)-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
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1. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.
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