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Chemical Structure : BRD7116
CAS No.: 329059-55-4
Catalog No.: PC-45539Not For Human Use, Lab Use Only.
BRD7116 selective inhibitor of leukemia stem cells (LSCs) via inhibition of HMG-CoA reductase (HMGCR).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | $398 | In stock | |
| 250 mg | Get quote |
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BRD7116 selective inhibitor of leukemia stem cells (LSCs) via inhibition of HMG-CoA reductase (HMGCR).
BRD7116 exhibits an EC50 of 200 nM for LSCe cells in co-culture.
BRD7116 shows limited activity against normal HSPCs and AML cell lines (>10 uM).
| M.Wt | 496.6614 | |
| Formula | C28H36N2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 48 mg/mL |
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| Chemical Name/SMILES |
Cyclopropanecarboxamide, N,N'-(sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl- (9CI) |
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1. Hartwell KA, et al. Nat Chem Biol. 2013 Dec;9(12):840-8.
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