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BRD 8184

Chemical Structure : BRD 8184

CAS No.: 1423058-83-6

BRD 8184 (BRD8184)

Catalog No.: PC-62465Not For Human Use, Lab Use Only.

BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM)..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM).

    Physicochemical Properties

    M.Wt 285.303
    Formula C15H15N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N1-hydroxy-N4-(2-(pyridin-4-yl)ethyl)terephthalamide

    References

    1. Wagner FF, et al. J Med Chem. 2013 Feb 28;56(4):1772-6.

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