BRD 8184 |CAS:1423058-83-6 Probechem Biochemicals

Chemical Structure : BRD 8184

BRD 8184 (BRD8184)

Catalog No.: PC-62465Not For Human Use, Lab Use Only.

BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM)..

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Biological Activity

BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM).

Physicochemical Properties

M.Wt	285.303
Formula	C15H15N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N1-hydroxy-N4-(2-(pyridin-4-yl)ethyl)terephthalamide

References

1. Wagner FF, et al. J Med Chem. 2013 Feb 28;56(4):1772-6.

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BRD 8184 (BRD8184)

Biological Activity

Physicochemical Properties

References

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