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BRD 8430

Chemical Structure : BRD 8430

CAS No.: 1482499-16-0

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BRD 8430 (BRD8430)

Catalog No.: PC-62467Not For Human Use, Lab Use Only.

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.
    BRD 8430 shows no activity against other HDACs.
    BRD 8430 decreases viability and induces differentiation of neuroblastoma cell lines.

    Physicochemical Properties

    M.Wt 573.738
    Formula C33H43N5O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(2-aminophenyl)-4-[[[(2R,3S)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl-methylamino]methyl]benzamide

    References

    1. Frumm SM, et al. Chem Biol. 2013 May 23;20(5):713-25.

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