BS148 |CAS:2162116-09-6 Probechem Biochemicals

Chemical Structure : BS148

BS148 (BS-148)

Catalog No.: PC-35305Not For Human Use, Lab Use Only.

BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1.

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Biological Activity

BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1.
BS148 specifically inhibits the growth of metastatic malignant melanoma cell lines without affecting normal human melanocytes.

Physicochemical Properties

M.Wt	361.606
Formula	C21H31NS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(1,4-dithiaspiro[4.5]decan-2-ylmethyl)-4-benzylpiperidine

References

1. Franchini S, et al. ChemMedChem. 2017 Nov 22;12(22):1893-1905.

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BS148 (BS-148)

Biological Activity

Physicochemical Properties

References

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