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Chemical Structure : BSJ-04-146
CAS No.: 2414478-45-6
Catalog No.: PC-20684Not For Human Use, Lab Use Only.
BSJ-04-146 is a potent, selective FAK PROTAC (IC50=26 nM), induces potent and durable FAK degradation in pancreatic and breast cancer cell lines at 10 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $288 | In stock | |
| 5 mg | $488 | In stock | |
| 10 mg | $788 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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BSJ-04-146 is a potent, selective FAK PROTAC (IC50=26 nM), induces potent and durable FAK degradation in pancreatic and breast cancer cell lines at 10 nM.
| M.Wt | 955.05 | |
| Formula | C50H57F3N8O8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-((2-((4-(1-(6-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)hexyl)piperidin-4-yl)-2-isopropoxy-5-methylphenyl)amino)-5-(trifluoromethyl)pyridin-4-yl)amino)-N-methylbenzamide |
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1. Eriko Koide, et al. Chembiochem. 2023 Apr 23;e202300141.
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