BSJ-04-175

Chemical Structure : BSJ-04-175

Catalog No.: PC-20683Not For Human Use, Lab Use Only.

BSJ-04-175 is a potent, selective focal adhesion kinase (FAK, protein tyrosine kinase 2 or PTK2) inhibitor with biochemical IC50 of 22 nM, 30-fold selectivity over PYK2.

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Biological Activity

BSJ-04-175 is a potent, selective focal adhesion kinase (FAK, protein tyrosine kinase 2 or PTK2) inhibitor with biochemical IC50 of 22 nM, 30-fold selectivity over PYK2.

Physicochemical Properties

M.Wt	541.62
Formula	C29H34F3N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(NC)C1=CC=CC=C1NC2=CC(NC3=CC(C)=C(C4CCNCC4)C=C3OC(C)C)=NC=C2C(F)(F)F

References

1. Eriko Koide, et al. Chembiochem. 2023 Apr 23;e202300141.

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BSJ-04-175

Biological Activity

Physicochemical Properties

References

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