BSP16 | STING agonist | Probechem Biochemicals

Chemical Structure : BSP16

BSP16 (LF250)

Catalog No.: PC-49313Not For Human Use, Lab Use Only.

BSP16 (LF250) is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer.

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Biological Activity

BSP16 is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer.
BSP16 could induce the "closed" conformation of STING. has an excellent pharmacokinetic profile as an oral drug, and induces tumor regression and durable antitumor immunity

Physicochemical Properties

M.Wt	369.275
Formula	C16H18O5Se
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-4-(5,6-dimethoxybenzo[b]selenophen-2-yl)-2-ethyl-4-oxobutanoic acid

References

1. Xi Feng, et al. J Med Chem. 2022 Sep 7. doi: 10.1021/acs.jmedchem.2c00634.

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BSP16 (LF250)

Biological Activity

Physicochemical Properties

References

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