You are here:Home-Chemical Inhibitors & Agonists-Immunology/Inflammation-STING-BSP16
BSP16

Chemical Structure : BSP16

CAS No.: 2727249-47-8

BSP16 (LF250)

Catalog No.: PC-49313Not For Human Use, Lab Use Only.

BSP16 (LF250) is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BSP16 is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer.
    BSP16 could induce the "closed" conformation of STING. has an excellent pharmacokinetic profile as an oral drug, and induces tumor regression and durable antitumor immunity

    Physicochemical Properties

    M.Wt 369.275
    Formula C16H18O5Se
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-4-(5,6-dimethoxybenzo[b]selenophen-2-yl)-2-ethyl-4-oxobutanoic acid

    References

    1. Xi Feng, et al. J Med Chem. 2022 Sep 7. doi: 10.1021/acs.jmedchem.2c00634.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: