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BSP16

Chemical Structure : BSP16

CAS No.: 2727249-47-8

BSP16 (LF250)

Catalog No.: PC-49313Not For Human Use, Lab Use Only.

BSP16 (LF250) is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BSP16 is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer. BSP16 could induce the "closed" conformation of STING. has an excellent pharmacokinetic profile as an oral drug, and induces tumor regression and durable antitumor immunity

Physicochemical Properties

M.Wt 369.275
Formula C16H18O5Se
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-4-(5,6-dimethoxybenzo[b]selenophen-2-yl)-2-ethyl-4-oxobutanoic acid

References

1. Xi Feng, et al. J Med Chem. 2022 Sep 7. doi: 10.1021/acs.jmedchem.2c00634.

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