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BTK inhibitor Compound I

Chemical Structure : BTK inhibitor Compound I

CAS No.: 1654727-21-5

BTK inhibitor Compound I

Catalog No.: PC-25074Not For Human Use, Lab Use Only.

BTK inhibitor Compound I is a potent, selective BTK inhibitor with IC50 of 0.415 nM, structural analog of Midobrutinib.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BTK inhibitor Compound I is a potent, selective BTK inhibitor with IC50 of 0.415 nM, structural analog of Midobrutinib.

Physicochemical Properties

M.Wt 466.89
Formula C21H19ClN8O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-N-(5-chlorobenzo[d]oxazol-2-yl)-1H-pyrazolo[3,4-d]pyrimidine-3-carboxamide

References

1. Patent WO2015022926 A1.

2. Patent WO2016121953 A1.

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