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Chemical Structure : BVL-GSK098
CAS No.: 2285440-39-1
Catalog No.: PC-49179Not For Human Use, Lab Use Only.
BVL-GSK098 (Alpibectir) is a small molecule able to inhibit Mycobacterium tuberculosis transcription regulator VirS, boosts bioactivation of ethionamide (ETH) and lower ETH MIC.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $218 | In stock | |
| 10 mg | $358 | In stock | |
| 25 mg | $588 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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BVL-GSK098 (Alpibectir) is a small molecule able to inhibit Mycobacterium tuberculosis transcription regulator VirS, boosts bioactivation of ethionamide (ETH) and lower ETH MIC.
BVL-GSK098 (Alpibectir) activates an EthA-independent-, VirS-dependent bioactivation pathway of ETH, makes ETH-resistant Mtb again susceptible to low ETH concentrations.
| M.Wt | 332.246 | |
| Formula | C12H14F6N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4,4,4-trifluoro-1-(3-(trifluoromethyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)butan-1-one |
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1. Patent WO2019034700 A1 2019-02-21.
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