BVT173187 | FPR1 inhibitor | Probechem Biochemicals

Chemical Structure : BVT173187

BVT173187 (BVT 173187)

Catalog No.: PC-20394Not For Human Use, Lab Use Only.

BVT173187 is a potent, selective, non-peptide inhibitor of formyl peptide receptor 1 (FPR1), inhibits fMLF and WKYMVM induced oxidase activity.

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Biological Activity

BVT173187 is a potent, selective, non-peptide inhibitor of formyl peptide receptor 1 (FPR1), inhibits fMLF and WKYMVM induced oxidase activity.
BVT173187 also affects signaling through the C5aR and CXCR (recognizing IL8).

Physicochemical Properties

M.Wt	330.59
Formula	C14H10Cl3NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3,5-dichloro-N-(2-chloro-5-methyl-phenyl)-2-hydroxy-benzamide

References

1. Hülya Cevik-Aras, et al. Biochem Pharmacol. 2012 Jun 15;83(12):1655-62.

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BVT173187 (BVT 173187)

Biological Activity

Physicochemical Properties

References

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