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Chemical Structure : Balicatib
CAS No.: 354813-19-7
Catalog No.: PC-21937Not For Human Use, Lab Use Only.
Balicatib (AAE581) is a potent, selective and orally active and selective cathepsin K inhibitor with IC50 of 22 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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Balicatib (AAE581) is a potent, selective and orally active and selective cathepsin K inhibitor with IC50 of 22 nM.
Balicatib (AAE581) displays 10-100-fold more potent in cell-based enzyme occupancy assays than cathepsin B, L, and S.
Balicatib (AAE581) stimulates periosteal bone formation in monkeys.
| M.Wt | 411.55 | |
| Formula | C23H33N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(4-propylpiperazin-1-yl)benzamide |
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1. Falgueyret JP, et al. J Med Chem. 2005 Dec 1;48(24):7535-43.
2. Jerome C, et al. Osteoporos Int. 2011 Dec;22(12):3001-11.
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