Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Vasopressin Receptor-Balovaptan
Balovaptan

Chemical Structure : Balovaptan

CAS No.: 1228088-30-9

Add to Favorites

Balovaptan (RG7314; RG-7314; RO5285119)

Catalog No.: PC-60033Not For Human Use, Lab Use Only.

Balovaptan (RG7314, RO5285119) is a potent, selective vasopressin-1 receptor antagonist with Kb of 0.39 nM at the human V1a receptor.

Packing Price Stock Quantity
10 mg $128 In stock
25 mg $218 In stock
50 mg $368 In stock
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Balovaptan (RG7314, RO5285119) is a potent, selective vasopressin-1 receptor antagonist with Kb of 0.39 nM at the human V1a receptor.
Balovaptan (RG7314, RO5285119)displays outstanding functional selectivity against human V2 (3888-fold) and OT (2735-fold) receptors.
Balovaptan (RG7314, RO5285119) also shows no significant off-target activities except for the human 5HT2B receptor in a diverse 120-target selectivity screen.

Physicochemical Properties

M.Wt 409.918
Formula C22H24ClN5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

8-chloro-5-methyl-1-{trans-4-[(pyridin-2-yl)oxy]cyclohexyl}-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

References

1. Schnider P, et al. J Med Chem. 2020 Feb 27;63(4):1511-1525.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: