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Bay 41-4109

Chemical Structure : Bay 41-4109

CAS No.: 298708-81-3

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Bay 41-4109 (Bay41-4109)

Catalog No.: PC-42040Not For Human Use, Lab Use Only.

Bay 41-4109 is a potent, non-nucleosidic inhibitor of HBV nucleocapsid maturation with IC50 of 0.05 uM.

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5 mg $118 In stock
10 mg $188 In stock
25 mg $298 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Bay 41-4109 is a potent, non-nucleosidic inhibitor of HBV nucleocapsid maturation with IC50 of 0.05 uM.
Bay 41-4109 reduces HBV core protein levels in cell culture, possess in vitro and in vivo antiviral activity.

Physicochemical Properties

M.Wt 395.7629
Formula C18H13ClF3N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 44 mg/mL
Chemical Name/SMILES

5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-, methyl ester, (4R)-

References

1. Deres K, et al. Science. 2003 Feb 7;299(5608):893-6.

2. Weber O, et al. Antiviral Res. 2002 May;54(2):69-78.

3. Brezillon N, et al. PLoS One. 2011;6(12):e25096.

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