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Becampanel

Chemical Structure : Becampanel

CAS No.: 188696-80-2

Becampanel (AMP 397)

Catalog No.: PC-61707Not For Human Use, Lab Use Only.

Becampanel (AMP 397) potent, competitive antagonist of the AMPA receptor (AMPAR) with IC50 of 11 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Becampanel (AMP 397) potent, competitive antagonist of the AMPA receptor (AMPAR) with IC50 of 11 nM; has anticonvulsant activity for the treatment of epilepsy, neuropathic pain and cerebral ischemia.

Epilepsy

Phase 2 Discontinued

Physicochemical Properties

M.Wt 330.191
Formula C10H11N4O7P
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((((7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)methyl)phosphonic acid

References

1. Kwan P, et al. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22.

2. Citraro R, et al. Expert Opin Ther Targets. 2014 Mar;18(3):319-34.

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