Chemical Structure : Bedaquiline
CAS No.: 843663-66-1
Catalog No.: PC-23456Not For Human Use, Lab Use Only.
Bedaquiline fumarate (TMC207, R207910) is a diarylquinoline antibiotic that targets ATP synthase, inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit.
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Bedaquiline fumarate (TMC207, R207910) is a diarylquinoline antibiotic that targets ATP synthase, inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit.
Bedaquiline is effective for the treatment of Mycobacterium tuberculosis infections.
M.Wt | 484.73 | |
Formula | C37H40 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol |
1. Jang JC, et al. J Microbiol. 2017 Apr 20.
2. Pang Y, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5).
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