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Bedaquiline fumarate

Chemical Structure : Bedaquiline fumarate

CAS No.: 845533-86-0

Bedaquiline fumarate (R403323;TMC207 fumarate;R207910 fumarate)

Catalog No.: PC-63299Not For Human Use, Lab Use Only.

Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections..

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Biological Activity

Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Bacterial Infection

Approved

Physicochemical Properties

M.Wt 671.588
Formula C36H35BrN2O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,2S)-1-(6-broMo-2-Methoxyquinolin-3-yl)-4-(diMethylaMino)-2-naphthalen-1-yl-1-phenylbutan-2-ol,(E)-but-2-enedioic acid

References

1. Jang JC, et al. J Microbiol. 2017 Apr 20.

2. Pang Y, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5).

3. Chahine EB, et al. Ann Pharmacother. 2014 Jan;48(1):107-15.

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