Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

You are here:Home-Chemical Inhibitors & Agonists-Tyrosine Kinase-EGFR-Befotertinib
Befotertinib

Chemical Structure : Befotertinib

CAS No.: 1835667-63-4

Befotertinib (D-0316, D0316)

Catalog No.: PC-38341Not For Human Use, Lab Use Only.

Befotertinib (D-0316) is an orally active, third-generation EGFR tyrosine kinase inhibitor that is selective for both EGFR-TKI sensitizing and T790M resistance mutations in NSCLC.

Packing Price Stock Quantity
5 mg $148 In stock
10 mg $228 In stock
25 mg $388 In stock
50 mg $598 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Befotertinib (D-0316) is an orally active, third-generation EGFR tyrosine kinase inhibitor that is selective for both EGFR-TKI sensitizing and T790M resistance mutations in NSCLC.

Physicochemical Properties

M.Wt 567.617
Formula C29H32F3N7O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide

References

1. Nagasaka M, et al. J Thorac Oncol. 2021 May;16(5):740-763.

2. Jian H, et al. Oncologist. 2022 Mar 11;27(3):163-e213.

3. Shun Lu, et al. Cancer Res (2021) 81 (13_Supplement): CT170.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: