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Belantamab

Chemical Structure : Belantamab

CAS No.:

Belantamab (Anti-human BCMA mAb, human IgG1-Kappa)

Catalog No.: PC-Ab1042Not For Human Use, Lab Use Only.

B-cell maturation antigen (BCMA) is a cell-surface receptor of the tumour necrosis superfamily required for plasma cell survival. BMCA is universally detected on patient-derived myeloma cells and has emerged as a selective antigen to be targeted by novel treatments in multiple myeloma. Belantamab mafodotin (belamaf.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

B-cell maturation antigen (BCMA) is a cell-surface receptor of the tumour necrosis superfamily required for plasma cell survival. BMCA is universally detected on patient-derived myeloma cells and has emerged as a selective antigen to be targeted by novel treatments in multiple myeloma. Belantamab mafodotin (belamaf; BLENREP, GSK2857916) is a first-in-class antibody–drug conjugate (ADC) that targets B-cell maturation antigen (BCMA).

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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