Chemical Structure : Belimumab
CAS No.:
Catalog No.: PC-Ab1086Not For Human Use, Lab Use Only.
Belimumab is a human IgG1λ monoclonal antibody that targets soluble human B lymphocyte stimulator proteins (BLyS, or BAFF and TNFSF13B). BLyS is unable to bind to receptors on B lymphocytes. The binding of BLyS to its receptor is essential for the survival of B lymphocytes. Consequently, belimumab reduces B-cell mediated immunity and the autoimmune response..
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Belimumab is a human IgG1λ monoclonal antibody that targets soluble human B lymphocyte stimulator proteins (BLyS, or BAFF and TNFSF13B). BLyS is unable to bind to receptors on B lymphocytes. The binding of BLyS to its receptor is essential for the survival of B lymphocytes. Consequently, belimumab reduces B-cell mediated immunity and the autoimmune response.
M.Wt | ||
Formula | Human IgG1 E239D, M241L-Human lambda3 K83R | |
Appearance | Solid | |
Storage |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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