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Chemical Structure : Beloranib
Catalog No.: PC-61441Not For Human Use, Lab Use Only.
Beloranib (ZGN-440) is an analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2) inhibitor.
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Beloranib (ZGN-440) is an analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2) inhibitor.
Beloranib (ZGN-440) strongly inhibit the growth of cancers in xenografted nude model.
Beloranib (ZGN-440) also causes significant body weight and appetite reduction an anti-obesity agent.
| M.Wt | 499.65 | |
| Formula | C29H41NO6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kim YM, et al. J Mol Endocrinol. 2007 Apr;38(4):455-65.
2. Morgen M, et al. ACS Chem Biol. 2016 Apr 15;11(4):1001-11.
3. Chun E, et al. Int J Cancer. 2005 Mar 10;114(1):124-30.
4. Hughes TE, et al. Obesity (Silver Spring). 2013 Sep;21(9):1782-8.
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