Chemical Structure : Beloranib
CAS No.:
251111-30-5
Beloranib
(CKD-732; ZGN-440)
Catalog No. : PC-61441Not For Human Use, Lab Use Only.
Beloranib (ZGN-440) is an analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2) inhibitor.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6144101
Biological Activity
Beloranib (ZGN-440) is an analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2 ) inhibitor.
Physicochemical Properties
M.Wt
499.65
Formula
C29H41NO6
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
[(3R,6R,7S,8S)-7-methoxy-8-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-2-oxaspiro[2.5]octan-6-yl] (E)-3-[4-[2-(dimethylamino)ethoxy]phenyl]prop-2-enoate
References
1. Kim YM, et al. J Mol Endocrinol.
2. Morgen M, et al. ACS Chem Biol.
3. Chun E, et al. Int J Cancer.
4. Hughes TE, et al. Obesity (Silver Spring).
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