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Chemical Structure : Benvitimod
CAS No.: 79338-84-4
Catalog No.: PC-60054Not For Human Use, Lab Use Only.
Benvitimod (GSK-2894512, Tapinarof) is a natural aryl hydrocarbon receptor (AhR) agonist with anti-inflammatory properties.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $28 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | $368 | In stock | |
| 250 mg | Get quote |
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Benvitimod (GSK-2894512, Tapinarof) is a natural aryl hydrocarbon receptor (AhR) agonist with anti-inflammatory properties.
Benvitimod binds and activates AhR in multiple cell types, moderates proinflammatory cytokine expression in stimulated peripheral blood CD4+ T cells and ex vivo human skin, and impacts barrier gene expression in primary human keratinocytes.
Benvitimod shows no impact on imiquimod-induced skin inflammation in AhR-deficient mice.
| M.Wt | 254.329 | |
| Formula | C17H18O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3,5-Dihydroxy-4-isopropylstilbene |
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1. Bissonnette R, et al. Arch Dermatol. 2010 Apr;146(4):446-9.
2. Bissonnette R, et al. J Eur Acad Dermatol Venereol. 2012 Dec;26(12):1516-21.
3. Smith SH,et al. J Invest Dermatol. 2017 Oct;137(10):2110-2119.
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