Chemical Structure : Benzamil hydrochloride
CAS No.: 161804-20-2
Catalog No.: PC-23671Not For Human Use, Lab Use Only.
Benzamil hydrochloride (Benzylamiloride hydrochloride) is an Amiloride analogue and Na+/Ca2+ exchanger (NCX) inhibitor with IC50 of 100 nM, also is a non-selective Deg/epithelial sodium channels (ENaC) blocker.
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Benzamil hydrochloride (Benzylamiloride hydrochloride) is an Amiloride analogue and Na+/Ca2+ exchanger (NCX) inhibitor with IC50 of 100 nM, also is a non-selective Deg/epithelial sodium channels (ENaC) blocker.
Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents with IC50 of 1.1 uM.
Benzamil hydrochloride could potentiate myogenic vasoconstriction.
| M.Wt | 356.21 | |
| Formula | C13H15Cl2N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3,5-Diamino-N-(N-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide hydrochloride |
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1. Fischer KG, et al.Nephrol Dial Transplant. 2002 Oct;17(10):1742-50.
2. Dai XQ, et al. Mol Pharmacol. 2007 Dec;72(6):1576-85.

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