Chemical Structure : Bersacapavir
CAS No.:
1638266-40-6
Bersacapavir
(JNJ 56136379, JNJ-6379)
Catalog No. : PC-20253Not For Human Use, Lab Use Only.
Bersacapavir (JNJ 56136379, JNJ-6379) is a potent HBV capsid assembly modulator, JNJ-6379 specifically and potently inhibits HBV replication with EC50 of 54 nM (HepG2.117 cells).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2025301
Biological Activity
Bersacapavir (JNJ 56136379, JNJ-6379) is a potent HBV capsid assembly modulator, JNJ-6379 specifically and potently inhibits HBV replication with EC50 of 54 nM (HepG2.117 cells).
Physicochemical Properties
M.Wt
418.37
Formula
C16H14F4N4O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-N-(3-cyano-4-fluorophenyl)-1-methyl-4-(N-(1,1,1-trifluoropropan-2-yl)sulfamoyl)-1H-pyrrole-2-carboxamide
References
1. Berke JM, et al. Antimicrob Agents Chemother
2. Zoulim F, et al. Gastroenterology
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