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Besifovir

Chemical Structure : Besifovir

CAS No.: 441785-25-7

Besifovir (ANA-380, LB-80380)

Catalog No.: PC-63285Not For Human Use, Lab Use Only.

Besifovir (ANA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Besifovir (ANA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).

Physicochemical Properties

M.Wt 299.23
Formula C10H14N5O4P
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((1-((2-Amino-9H-purin-9-yl)methyl)cyclopropoxy)methyl)phosphonic acid

References

1. Choi JR, et al. J Med Chem. 2004 May 20;47(11):2864-9.

2. Yuen MF, et al. Hepatology. 2010 Mar;51(3):767-76.

3. Papatheodoridis GV, et al. Curr Opin Mol Ther. 2006 Aug;8(4):352-7.

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