Catalog No.: PC-42639Not For Human Use, Lab Use Only.
Betulinic acid (Betulic acid) is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.
Betulinic acid (Betulic acid) is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.
Betulinic acid shows to be a catalytic inhibitor of Topo II with IC50 values ranging from 0.38 to 58 uM.
Betulinic acid induces cell death through induction of apoptosis and inhibition of autophagic flux in microglia BV-2 cells.
Physicochemical Properties
M.Wt
456.7003
Formula
C30H48O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β)-
References
1. Potze L, et al. Cell Death Dis. 2014 Apr 10;5:e1169.
2. Seo J, et al. Biomol Ther (Seoul). 2017 Mar 10. doi: 10.4062/biomolther.2016.255.
3. Wada S, et al. Chem Biodivers. 2005 May;2(5):689-94.
