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Chemical Structure : Bevirimat
CAS No.: 174022-42-5
Catalog No.: PC-22328Not For Human Use, Lab Use Only.
Bevirimat (PA-457) is a potent HIV inhibitor that inhibits HIV Gag protein processing and viral maturation.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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Bevirimat (PA-457) is a potent HIV inhibitor that inhibits HIV Gag protein processing and viral maturation.
Bevirimat (PA-457) potently inhibits replication of both WT and drug-resistant HIV-1 isolates.
Bevirimat (PA-457) demonstrate that the compound acts by disrupting a late step in Gag processing involving conversion of the capsid precursor (p25) to mature capsid protein (p24).
Bevirimat (PA-457) is a specific inhibitor of capsid precursor, CA-SP1.
| M.Wt | 584.84 | |
| Formula | C36H56O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-carboxy-3-methylbutanoyl)oxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid |
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1. Li F, et al. Virology. 2006 Dec 5-20;356(1-2):217-24.
2. Li F, et al. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13555-60.
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