Chemical Structure : Bioymifi
CAS No.: 1420071-30-2
Catalog No.: PC-45466Not For Human Use, Lab Use Only.
Bioymifi is a potent small-molecule activatior of the TRAIL receptor DR5, directly binds to DR5 with Kd of 1.2 uM.
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Bioymifi is a potent small-molecule activatior of the TRAIL receptor DR5, directly binds to DR5 with Kd of 1.2 uM.
Bioymifi shows little binding affinity to the DR4 ECD.
Bioymifi promotes DR5 aggregation, activation and induces apoptosis.
M.Wt | 494.3174 | |
Formula | C22H12BrN3O4S | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: 23.5 mg/mL |
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Chemical Name/SMILES |
1H-Isoindole-1,3(2H)-dione, 5-[5-[[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]- |
1. Wang G, et al. Nat Chem Biol. 2013 Feb;9(2):84-9.
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