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Chemical Structure : Bis-T-23
Catalog No.: PC-63280Not For Human Use, Lab Use Only.
Bis-T-23 is a small molecule that stimulates actin-dependent dynamin oligomerization and promotes dynamin GTPase activity, increases actin polymerization in injured podocytes.
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Bis-T-23 (Ryngo 1-23) is a small molecule that stimulates actin-dependent dynamin oligomerization and promotes dynamin GTPase activity, increases actin polymerization in injured podocytes.
Bis-T-23 ameliorates or prevents proteinuria and diminishes mesangial matrix expansion in diverse genetic and chronic models of glomerular disease in rodents.
Bis-T-23 improves renal health in diverse models of both transient kidney disease and CKD.
| M.Wt | 480.433 | |
| Formula | C23H20N4O8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Schiffer M, et al. Nat Med. 2015 Jun;21(6):601-9.
2. Del Nogal-Avila M, et al. Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F63-5.
3. Gu C, et al. J Am Soc Nephrol. 2017 Feb;28(2):446-451.
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