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Bisnorcymserine

Chemical Structure : Bisnorcymserine

CAS No.: 219920-81-7

Bisnorcymserine ((-)-Bisnorcymserine)

Catalog No.: PC-26807Not For Human Use, Lab Use Only.

Bisnorcymserine ((-)-Bisnorcymserine) is a potent inhibitor for butyrylcholinesterase (BChE) with IC50 of 0.228 nM, reduces the levels of amyloid-β peptide (Aβ), exhibits ameliorates AD in elderly rat models.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Bisnorcymserine ((-)-Bisnorcymserine) is a potent inhibitor for butyrylcholinesterase (BChE) with IC50 of 0.228 nM, reduces the levels of amyloid-β peptide (Aβ), exhibits ameliorates AD in elderly rat models.

Physicochemical Properties

M.Wt 351.45
Formula C21H25N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3aS,8aR)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-isopropylphenyl)carbamate

References

1. Kamal MA, et al. J Alzheimers Dis. 2006 Sep;10(1):43-51.

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