Bitopertin R enantiomer |CAS:845614-12-2 Probechem Biochemicals

Chemical Structure : Bitopertin R enantiomer

Catalog No.: PC-42707Not For Human Use, Lab Use Only.

Bitopertin R enantiomer is the R-enantiomer of Bitopertin, which is a potent and selective GlyT1 inhibitor with EC50 of 54 nM.

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Biological Activity

Bitopertin R enantiomer is the R-enantiomer of Bitopertin, which is a potent and selective GlyT1 inhibitor with EC50 of 54 nM.

M.Wt	543.455
Formula	C21H20F7N3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methanone, [4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl][5-(methylsulfonyl)-2-[(1R)-2,2,2-trifluoro-1-methylethoxy]phenyl]-

1. Pinard E, et al. J Med Chem. 2010 Jun 24;53(12):4603-14.

2. Alberati D, et al. Neuropharmacology. 2012 Feb;62(2):1152-61

3. Martin-Facklam M, et al. Neuropsychopharmacology. 2013 Feb;38(3):504-12.