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Blarcamesine

Chemical Structure : Blarcamesine

CAS No.: 195615-83-9

Blarcamesine (Anavex-73;AE37;ANAVEX 2-73;AVex-73)

Catalog No.: PC-36088Not For Human Use, Lab Use Only.

ANAVEX2-73 (Blarcamesine) is a Sigma-1 receptor agonist with IC50 of 860 nM, and muscarinic receptor modulator with neuroprotective effects.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ANAVEX2-73 (Blarcamesine) is a Sigma-1 receptor agonist with IC50 of 860 nM, and muscarinic receptor modulator with neuroprotective effects.

    Physicochemical Properties

    M.Wt 281.399
    Formula C19H23NO
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(2,2-diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine

    References

    1. Lahmy V, et al. Neuropsychopharmacology. 2013 Aug;38(9):1706-23. 
    2. Ye N, et al. J Med Chem. 2020 Dec 24;63(24):15187-15217.

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