Boditrectinib | pan-TRK inhibitor | Probechem Biochemicals

Chemical Structure : Boditrectinib

Boditrectinib (AUM-601, NOV1601, HL5101, CHC-2014)

Catalog No.: PC-20024Not For Human Use, Lab Use Only.

Boditrectinib (AUM-601, NOV1601, HL5101, CHC-2014) is a highly selective, orally administered, which inhibits not only pan-TRK (TRKA, TRKB, and TRKC), but also resistance mutations of TRKs.

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Biological Activity

Boditrectinib (AUM-601, NOV1601, HL5101, CHC-2014) is a highly selective, orally administered, which inhibits not only pan-TRK (TRKA, TRKB, and TRKC), but also resistance mutations of TRKs.

Physicochemical Properties

M.Wt	438.48
Formula	C23H24F2N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R,E)-3-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-1-(piperazin-1-yl)prop-2-en-1-one

References

1. Patent US20160168156.

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Boditrectinib (AUM-601, NOV1601, HL5101, CHC-2014)

Biological Activity

Physicochemical Properties

References

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