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Brenipatide

Chemical Structure : Brenipatide

CAS No.: 2408921-49-1

Brenipatide (LY-3537031, LY3537031)

Catalog No.: PC-28508Not For Human Use, Lab Use Only.

Brenipatide (LY-3537031) is a potent, dual-agonist of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, targets central nervous system and inflammatory pathways that include receptors linked to reward and addiction in the brain.

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Biological Activity

Brenipatide (LY-3537031) is a potent, dual-agonist of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, targets central nervous system and inflammatory pathways that include receptors linked to reward and addiction in the brain.

Physicochemical Properties

M.Wt 4891.52
Formula C228H354N46O72
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

{d-Tyr}-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Leu(aMe)}-Leu-Asp-Lys-{Lys(AEEA-AEEA-γGlu-C20 diacid)}-Ala-Gln-{Aib}-Glu-Phe-Ile-Glu-{Tyr(aMe)}-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

References

1. Neumann J, et al. Pharmaceutics. 2026 Apr 06;18(4):447.

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