Chemical Structure : Briciclib
CAS No.: 865783-99-9
Catalog No.: PC-21264Not For Human Use, Lab Use Only.
Briciclib (ON 014185) is a small molecule inhibitor of eukaryotic translation initiation factor 4E (eIF4E), downregulates the expression of eIF4E and its two complex partners eIF4A and G, as well as other eIFs (e.g. eIF1A, eIF2α, eIF3A, eIF3B, eIF5 and eIF6).
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10 mg | $128 | In stock | |
25 mg | $218 | In stock | |
50 mg | $368 | In stock | |
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Briciclib (ON 014185) is a small molecule inhibitor of eukaryotic translation initiation factor 4E (eIF4E), downregulates the expression of eIF4E and its two complex partners eIF4A and G, as well as other eIFs (e.g. eIF1A, eIF2α, eIF3A, eIF3B, eIF5 and eIF6).
M.Wt | 474.42 | |
Formula | C19H23O10PS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Phenol, 2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]-, 1-(dihydrogen phosphate) |
1. Nicole Golob-Schwarzl, et al. J Invest Dermatol. 2023 Oct 19:S0022-202X(23)02917-2.
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