Bupropion hydrochloride | DAT/NET inhibitor

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Chemical Structure : Bupropion hydrochloride

CAS No.: 31677-93-7

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Bupropion hydrochloride (Amfebutamone hydrochloride)

Catalog No.: PC-28177Not For Human Use, Lab Use Only.

Bupropion hydrochloride (Amfebutamone) is an orally active, norepinephrine-dopamine reuptake inhibitor (NDRI), blocks dopamine (DA) uptake and Methamphetamine-induced DA release with IC50s of 1.76 uM and 14.2 uM, respectively, shows antidepressant activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	276.20
Formula	C13H19Cl2NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1)

References

1. Linda D Simmler, et al. BMC Res Notes. 2013 Jun 5;6:220.

2. Piotr Tutka, et al. Eur J Pharmacol. 2004 Sep 19;499(1-2):117-20.

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Bupropion hydrochloride (Amfebutamone hydrochloride)

Biological Activity

Physicochemical Properties

References

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