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Burimamide

Chemical Structure : Burimamide

CAS No.: 34970-69-9

Burimamide (SK&F 92058)

Catalog No.: PC-61568Not For Human Use, Lab Use Only.

Burimamide is a potent dual H3/H2 receptor antagonist with Ki of 0.07 and 7.8 uM, respectively.

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    Biological Activity

    Burimamide is a potent dual H3/H2 receptor antagonist with Ki of 0.07 and 7.8 uM, respectively.
    Burimamideshows weak affinity for H1, and has antinociceptive effects in vivo.

    Physicochemical Properties

    M.Wt 212.32
    Formula C9H16N4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea

    References

    1. Wyllie JH, et al. Lancet. 1972 Nov 25;2(7787):1117-20.

    2. Ambache N, et al. Br J Pharmacol. 1973 Jun;48(2):362P-363P.

    3. Capurro N, et al. Br J Pharmacol. 1973 Aug;48(4):620-8.

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