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Butenafine hydrochloride

Chemical Structure : Butenafine hydrochloride

CAS No.: 101827-46-7

Butenafine hydrochloride (KP363 hydrochloride)

Catalog No.: PC-45219Not For Human Use, Lab Use Only.

A synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.

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Biological Activity

Butenafine (KP363) is a synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.
Butenafine displays superior activity against Candida albicans than terbinafine and naftifine.
Butenafine demonstrates low MICs against Cryptococcus and Aspergillus.

Physicochemical Properties

M.Wt 353.9281
Formula C23H28ClN
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride (1:1)

References

1. Singal A. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):999-1005.

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