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Chemical Structure : C-5401331
Catalog No.: PC-21719Not For Human Use, Lab Use Only.
C-5401331 is a small molecule T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) inhibitor, suppresses acute myeloid leukemia (AML) cell proliferation.
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C-5401331 is a small molecule T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) inhibitor, suppresses acute myeloid leukemia (AML) cell proliferation.
C-5401331 inhibits cell viability of THP-1 and HL-60 AML cells with IC50 of 206.6 nM and 318.10 nM respectively.
C-5401331 inhibits Tim-3 and induces early and late phase apoptosis in AML cells.
| M.Wt | 332.36 | |
| Formula | C24H12O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Al Shahrani M, et al. Med Oncol. 2024 Jan 24;41(3):63.
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