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C. difficile inhibitor 57

Chemical Structure : C. difficile inhibitor 57

CAS No.:

C. difficile inhibitor 57

Catalog No.: PC-21216Not For Human Use, Lab Use Only.

C. difficile inhibitor 57 is a potent, selective, narrow-spectrum antibacterial against Clostridioides difficile with MIC50 of 0.5 ug/mL, targets cell-wall synthesis.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

C. difficile inhibitor 57 is a potent, selective, narrow-spectrum antibacterial against Clostridioides difficile with MIC50 of 0.5 ug/mL, targets cell-wall synthesis.
C. difficile inhibitor 57 is not active against representative gut bacteria or other Gram-positive and Gram-negative bacteria, including MRSA.

Physicochemical Properties

M.Wt 341.33
Formula C16H15N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-(cyclopentyloxy)phenyl)-5-(4-nitro-1H-imidazol-2-yl)-1,2,4-oxadiazole

References

1. Qian Y, et al. J Med Chem. 2023 Sep 21. doi: 10.1021/acs.jmedchem.3c01249.

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