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Chemical Structure : C10-AMS
Catalog No.: PC-22699Not For Human Use, Lab Use Only.
C10-AMS is an acyl adenylate mimic and acyl-acyl carrier protein synthetase (AasS, acyl-ACP synthetase) inhibitor with Ki of 0.6 uM, inhibit the AasS-catalyzed loading of fatty acids onto acyl carrier protein (ACP).
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C10-AMS is an acyl adenylate mimic and acyl-acyl carrier protein synthetase (AasS, acyl-ACP synthetase) inhibitor with Ki of 0.6 uM, inhibit the AasS-catalyzed loading of fatty acids onto acyl carrier protein (ACP).
C10-AMS is able to effectively stop in vitro loading of decanoic acid onto ACPs from E. coli and V. cholerae by inhibiting AasS from both V. harveyi and V. cholerae.
C10-AMS can be used to study fatty acid recycling in other bacteria as more AasS enzymes continue to be annotated and provides a platform for potential antibiotic development.
| M.Wt | 486.59 | |
| Formula | C20H34N6O6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Currie MF, et al. Sci Rep. 2020 Oct 20;10(1):17776.
2. Huang H, et al. PLoS Pathog. 2024 Jul 15;20(7):e1012376.
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